
Publications
2024
Evolution of diapause in the African turquoise killifish by remodeling the ancient gene regulatory landscape. Singh PP, Reeves GA, Contrepois K, Papsdorf K, Miklas JW, Ellenberger M, Hu CK, Snyder MP, & Brunet A. Cell. 2024;187(13):3338-3356.e30. doi:10.1016/j.cell.2024.04.048 pdf
2023
The CRTC-1 transcriptional domain is required for COMPASS complex-mediated longevity in C. elegans. Silva-García CG, Láscarez-Lagunas LI, Papsdorf K, Heintz C, Prabhakar A, Morrow CS, Pajuelo Torres L, Sharma A, Liu J, Colaiácovo MP, Brunet A, Mair WB. Nat Aging. 2023 Nov;3(11):1358-1371. doi: 10.1038/s43587-023-00517-8. Epub 2023 Nov 9.PMID: 37946042 pdf
Lipid droplets and peroxisomes are co-regulated to drive lifespan extension in response to mono-unsaturated fatty acids. Papsdorf K, Miklas JW, Hosseini A, Cabruja M, Morrow CS, Savini M, Yu Y, Silva-García CG, Haseley NR, Murphy LM, Yao P, de Launoit E, Dixon SJ, Snyder MP, Wang MC, Mair WB, Brunet A.Nat Cell Biol. 2023 May;25(5):672-684. doi: 10.1038/s41556-023-01136-6. Epub 2023 May 1.PMID: 37127715 pdf
2021
In-depth triacylglycerol profiling using MS3 Q-Trap mass spectrometry. Cabruja M, Priotti J, Domizi P, Papsdorf K, Kroetz DL, Brunet A, Contrepois K, Snyder MP.Anal Chim Acta. 2021 Nov 1;1184:339023. doi: 10.1016/j.aca.2021.339023. Epub 2021 Sep 3.PMID: 34625255 pdf
2019
head-bent resistant Hsc70 variants show reduced Hsp40 affinity and altered protein folding activity. Papsdorf K, Sima S, Schmauder L, Peter S, Renner L, Hoffelner P, Richter K.Sci Rep. 2019 Aug 16;9(1):11955. doi: 10.1038/s41598-019-48109-0.PMID: 31420580 pdf
2018
Cross-Platform Comparison of Untargeted and Targeted Lipidomics Approaches on Aging Mouse Plasma. Contrepois K, Mahmoudi S, Ubhi BK, Papsdorf K, Hornburg D, Brunet A, Snyder M.Sci Rep. 2018 Dec 10;8(1):17747. doi: 10.1038/s41598-018-35807-4.PMID: 30532037 pdf
2016 and before
Construction and evaluation of yeast expression networks by database-guided predictions. Papsdorf K, Sima S, Richter G, Richter K.Microb Cell. 2016 Apr 21;3(6):236-247. doi: 10.15698/mic2016.06.505.PMID: 28357360 pdf
Polyglutamine toxicity in yeast induces metabolic alterations and mitochondrial defects. Papsdorf K, Kaiser CJ, Drazic A, Grötzinger SW, Haeßner C, Eisenreich W, Richter K.BMC Genomics. 2015 Sep 3;16(1):662. doi: 10.1186/s12864-015-1831-7.PMID: 26335097 pdf
The balanced regulation of Hsc70 by DNJ-13 and UNC-23 is required for muscle functionality. Papsdorf K, Sacherl J, Richter K.J Biol Chem. 2014 Sep 5;289(36):25250-61. doi: 10.1074/jbc.M114.565234. Epub 2014 Jul 22.PMID: 2505341 pdf
Chaperone-interacting TPR proteins in Caenorhabditis elegans. Haslbeck V, Eckl JM, Kaiser CJ, Papsdorf K, Hessling M, Richter K.J Mol Biol. 2013 Aug 23;425(16):2922-39. doi: 10.1016/j.jmb.2013.05.019. Epub 2013 May 29.PMID: 23727266
A network of genes connects polyglutamine toxicity to ploidy control in yeast. Kaiser CJ, Grötzinger SW, Eckl JM, Papsdorf K, Jordan S, Richter K.Nat Commun. 2013;4:1571. doi: 10.1038/ncomms2575.PMID: 23481379 pdf
The lid domain of Caenorhabditis elegans Hsc70 influences ATP turnover, cofactor binding and protein folding activity. Sun L, Edelmann FT, Kaiser CJ, Papsdorf K, Gaiser AM, Richter K.PLoS One. 2012;7(3):e33980. doi: 10.1371/journal.pone.0033980. Epub 2012 Mar 29.PMID: 22479492 pdf